Theralase® Granted Canadian Patent for Metal-Glycoprotein Complexes Used to Hunt Cancer Cells and When Laser Light Activated Destroy Them Toronto, Ontario – November 15, 2018 Theralase Technologies Inc. (“Theralase®” or the “Company”) (TSXV: TLT) (OTCQB: TLTFF), a clinical stage pharmaceutical company dedicated to the research and development of light activated Photo Dynamic Compounds (“PDCs”) and their associated drug formulations, used to safely and effectively destroy various cancers is pleased to announce that it has been granted a Canadian patent protecting its unique metal-glycoprotein complexes used to hunt cancer cells and when laser light activated destroy them.  The Canadian patent entitled, “Metal-Glycoprotein Complexes And Their Use As Chemotherapeutic Compounds” is critical in protecting Theralase’s systemic and targeted anti-cancer therapies to allow PDCs and their associated drug formulations to be systemically injected to hunt and destroy cancer cells for various cancer conditions.  Arkady Mandel, M.D., Ph.D., D.Sc., Interim Chief Executive Officer and … Read More

Toronto, Ontario – November 29, 2018 “Theralase®” or the “Company” (TSXV: TLT) (OTCQB: TLTFF), a clinical stage pharmaceutical company dedicated to the research and development of light activated Photo Dynamic Compounds (“PDCs”) and their associated drug formulations intended to safely and effectively destroy cancer released its 3Q2018 financial statements.  Total revenue for the nine-month period ended September 30, 2018 decreased to $1,276,630 from $1,354,254 for the same period in 2017, a 6% decrease. In Canada, revenue decreased 19% to $847,870 from $1,046,508. In the US, revenue decreased 7% to $253,742 from $272,305 and international revenue increased 393% to $175,018 from $35,441. The increase in international revenue in 2018 and the corresponding decrease in Canadian and US revenue is attributable to the Company hiring an International Sales Manager and restructuring the Canadian and US sales and marketing departments.  Cost of sales for the nine-month period ended September 30, 2018 was $559,296 … Read More

Theralase® Provides Update on 9 months Post Treatment Cystoscopy Analysis Toronto, Ontario – November 8, 2018 Theralase Technologies Inc. (“Theralase®” or the “Company”) (TSXV: TLT) (OTCQB: TLTFF), a clinical stage pharmaceutical company dedicated to the research and development of light activated Photo Dynamic Compounds (“PDCs”) and their associated drug formulations intended to safely and effectively destroy various cancers has provided an update on patient five, enrolled and treated in the recently completed Phase Ib Non-Muscle Invasive Bladder Cancer (“NMIBC”) clinical study (“Study”).  The Study’s purpose was to evaluate TLD-1433, Theralase’s lead PDC, for the primary endpoint of safety and tolerability, with a secondary endpoint of pharmacokinetics (movement and exit of drug within tissue) and an exploratory endpoint of efficacy.  Theralase’s Anti-Cancer Treatment involves the instillation of a water-based solution of Theralase’s lead anti-cancer PDC, TLD-1433 at the Therapeutic Dose (0.70 mg/cm2), via a catheter inserted through the urethra into the … Read More

Toronto, Ontario – October 3, 2018 Theralase Technologies Inc. (“Theralase” or “Company”) (TSXV: TLT) (OTCQX: TLTFF) is pleased to announce that it has closed its previously announced non-brokered private placement offering (the “Offering”) of units (“Unit”).  On closing, the Corporation issued an aggregate of 3,157,059 Units at a price of $0.35 per Unit for aggregate gross proceeds of approximately $1,104,970.  Each Unit consists of one common share of the Company (“Common Share”) and one common share purchase warrant (“Warrant”). Each Warrant entitles the holder to acquire an additional Common Share at an exercise price of $0.50 per share for a period of 24 months following the date of issuance. The Company intends to use the proceeds of the Offering for the following: – Advancement of Phase II Non-Muscle Invasive Bladder Cancer clinical study – Working capital and general corporate purposes   The securities offered have not been registered under the … Read More

Theralase® Affiliated Researchers Present New Data that Demonstrates the Application of Theralase’s Lead Photo Dynamic Compound, TLD-1433, in the Destruction of Gastrointestinal Dysplasia and Esophageal Cancer. Toronto, Ontario – October 9, 2018 Theralase Technologies Inc. (“Theralase®” or the “Company”) (TSXV: TLT) (OTCQX: TLTFF), a clinical stage pharmaceutical company dedicated to the research and development of light activated Photo Dynamic Compounds (“PDCs”) and their associated drug formulations intended to safely and effectively destroy various cancers announced today that Theralase affiliated researchers have presented immunohistochemical analytical data supporting the use of TLD-1433 Photo Dynamic Therapy (“PDT”) in the destruction of gastrointestinal dysplasia and esophageal cancer. Esophageal carcinoma, including Squamous Cell Carcinoma (“SCC”) and adenocarcinoma, is a leading cause of cancer related deaths worldwide. While SCC arises through progression from Low Grade Dysplasia (“LGD”) to High Grade Dysplasia (“HGD”), adenocarcinoma is preceded by Barrett’s metaplasia followed by low and then high grade dysplastic changes. There … Read More

Toronto, Ontario – September 10, 2018 Theralase Technologies Inc. (“Theralase®” or the “Company”) (TSXV: TLT) (OTCQX: TLTFF), a clinical stage pharmaceutical company dedicated to the research and development of light activated Photo Dynamic Compounds (“PDCs”) and their associated drug formulations, intended to safely and effectively destroy various cancers, announced today that Health Canada has approved the Company’s Clinical Trial Application (“CTA”), allowing clinical study evaluation of Theralase’s lead anti-cancer drug, TLD-1433. The CTA approval allows Theralase to authorize clinical oncology sites in Canada to enroll and treat patients in a pivotal Phase II Non-Muscle Invasive Bladder Cancer (“NMIBC”) clinical study (“Study II”), pending Health Canada Investigational Testing Authorization (“ITA”) for the Theralase TLC-3200 Medical Laser System and Research Ethics Board (“REB”) approval, both expected in due course. Study II titled, “A Phase II Clinical Study of Intravesical Photo Dynamic Therapy in Patients with BCG-Unresponsive Non-Muscle Invasive Bladder Cancer or Patients … Read More

Theralase® Researchers Invited to Present at International Conference in Germany Toronto, Ontario – September 4, 2018 Theralase Technologies Inc. (“Theralase” or the “Company”) (TSXV: TLT) (OTCQX: TLTFF), a clinical stage pharmaceutical company dedicated to the research and development of light activated Photo Dynamic Compounds (“PDCs”) and their associated drug formulations intended to safely and effectively destroy various cancers announced today that Theralase® researchers have been invited to present their latest research at the international conference, “Photodynamic Therapy and Photodiagnostics Update” to be held in Kochel am See (near Munich, Germany) on September  18 to 22, 2018. The “Photodynamic Therapy and Photodiagnostics Update” conference is a highly regarded event in the field of Photo Dynamic Therapy (“PDT”) bringing together researchers and clinicians working in all fields of PDT and Photo Diagnosis (“PD”) to foster scientific development of this technology in the fields of biology and medicine. Arkady Mandel, MD, PhD, DSc., Interim … Read More

Not for distribution to U.S. news wire services or dissemination in the United States. Toronto, Ontario – August 28, 2018 Theralase Technologies Inc. (the “Theralase” or “Company”) (TSXV: TLT) (OTCQX: TLTFF), a clinical stage pharmaceutical company dedicated to the research and development of light activated Photo Dynamic Compounds and their associated drug formulations to safely and effectively destroy various cancers, is pleased to announce that it proposes to conduct a non-brokered private placement offering of up to 28,571,429 units at a price of $0.35 per unit for gross proceeds of up to $10 million.  Each unit will consist of one common share of the Company and one common share purchase warrant with each warrant entitling the holder to purchase one common share at an exercise price of $0.50 per share for a period of 24 months. The Company intends to use the proceeds of the offering for the following: – … Read More

Theralase® Provides Update on Upcoming Initiatives for Phase II Non-Muscle Invasive Bladder Cancer Clinical Study Toronto, Ontario – August 27, 2018 Theralase Technologies Inc. (“Theralase®” or the “Company”) (TSXV: TLT) (OTCQX: TLTFF), a clinical stage pharmaceutical company dedicated to the research and development of light activated Photo Dynamic Compounds (“PDCs”) and their associated drug formulations intended to safely and effectively destroy various cancers has provided a corporate update on the Phase II for the Non-Muscle Invasive Bladder Cancer (“NMIBC”) Clinical Study. Photo Dynamic Therapy (“PDT”) utilizing the Company’s lead drug, TLD-1433, has met all expectations of the Company in the successfully completed Phase Ib NMIBC Clinical Study. In the Phase Ib study all 6 patients enrolled and treated (3 at the Maximum Recommended Starting Dose (“MRSD”) (0.35 mg/cm2) and 3 at the Therapeutic Dose (0.70 mg/cm2)) achieved both the primary (safety and tolerability as measured by Adverse Events (“AE”)) and … Read More

Toronto, Ontario – August 20, 2018 Theralase Technologies Inc. (“Theralase®” or the “Company”) (TSXV: TLT) (OTCQX: TLTFF), a clinical stage pharmaceutical company dedicated to the research and development of light activated Photo Dynamic Compounds (“PDCs”) and their associated drug formulations intended to safely and effectively destroy various cancers has submitted a Clinical Trial Application (“CTA”) and Investigational Testing Authorization (“ITA”) for its TLD-1433 anti-cancer technology to Health Canada for review and approval. Pending Health Canada and the individual Canadian oncology location(s) Research Ethics Board’s (“REB”) approvals, and subject to securing the requisite financing, Theralase plans to commence a Phase II Non-Muscle Invasive Bladder Cancer (“NMIBC”) clinical study, entitled, “Photo Dynamic Therapy Using Laser Light Activated TLD-1433 in BCG-Unresponsive Patient Population” (“Study”) with select Canadian oncology locations. Theralase’s anti-cancer technology utilizes the proprietary Theralase TLC-3200 Medical Laser System to light activate the Company’s lead, patented PDC, TLD-1433, intended to treat NMIBC. … Read More