Toronto, Ontario – March 27, 2018 Theralase Technologies Inc. (“Theralase®” or the “Company”) (TSXV: TLT) (OTCQX: TLTFF), a clinical stage pharmaceutical company dedicated to the research and development of light activated Photo Dynamic Compounds (“PDCs”) and their associated drug formulations to safely and effectively destroy various cancers, announced the filing of a US patent application detailing the discovery of a significant increase in the destruction of cancer cells, when Theralase’s patented anti-cancer technology is combined with cannabinoids. In preclinical experiments, Theralase® scientific researchers combined a specific cannabinoid with their patented anti-cancer Photo Dynamic Therapy (“PDT”) technology to produce an unexpected synergistic effect in the destruction of rat glioma brain cancer cells (“RG2”). In the study, RG2 brain cancer cells were preconditioned, in-vitro, with a specific cannabinoid and then subjected to Theralase’s anti-cancer technology. The researchers discovered that the efficacy of this combined treatment increased 250%, compared to treatment with Theralase’s … Read More

Toronto, Ontario – March 15, 2018 Theralase Technologies Inc. (“Theralase®” or the “Company”) (TSXV: TLT) (OTCQX: TLTFF), a clinical stage pharmaceutical company dedicated to the research and development of light activated Photo Dynamic Compounds (“PDCs”) and their associated drug formulations to safely and effectively destroy various cancers, announced today that its lead PDC, TLD-1433, combined with transferrin to form Rutherrin®, has been demonstrated to effectively destroy human brain cancer stem cells. Despite tremendous advances in cancer therapy over the last ten years, resistance to treatment and high rates of recurrence remain stubbornly common. In fact, even patients who experience a complete clinical response to frontline therapy (i.e.: surgery, radiation or chemotherapy), often suffer a relapse with the emergence of lethal, drug-resistant disease—stemming in large part from microscopic deposits of surviving cancer cells that escaped treatment by various mechanisms. This is commonplace for malignancies of the bladder and brain. The contribution of … Read More

Toronto, Ontario – March 7, 2018 Theralase Technologies Inc. (“Theralase®” or the “Company”) (TSXV: TLT) (OTCQX: TLTFF), a clinical stage pharmaceutical company dedicated to the research and development of light activated Photo Dynamic Compounds (“PDCs”) and their associated drug formulations to safely and effectively destroy various cancers, announced today that it has been notified that it has been granted allowance for a Canadian patent to issue later this year for Rutherrin® (TLD-1433 PDC combined with transferrin) for the treatment of cancer. Arkady Mandel, M.D., Ph.D., D.Sc., Interim Chief Executive Officer and Chief Scientific Officer of Theralase® and the inventor of the technology stated that; “Allowance of one of the Company’s key patents is timely as we approach the completion of enrollment in our Phase Ib trial for Non-Muscle Invasive Bladder Cancer (“NMIBC”). If successful, the Company looks forward to commencing Phase II NMIBC clinical study. The Company is currently completing … Read More

Toronto, Ontario – March 5, 2018 Theralase Technologies Inc. (“Theralase®” or the “Company”) (TSXV: TLT) (OTCQX: TLTFF), a clinical stage pharmaceutical company dedicated to the research and development of light activated Photo Dynamic Compounds (“PDCs”) and their associated drug formulations to safely and effectively destroy various cancers announced today that its lead compound, TLD-1433, when combined with transferrin to form Rutherrin®, has been demonstrated to target and effectively kill human lung cancer cells, in two preclinical animal models. According to the American Cancer Society, lung cancer is the second most common cancer in both men and women, next to skin cancer, with about 14% of all new cancers diagnosed as lung cancer. Lung cancer is by far the leading cause of cancer death among both men and women. Each year, more people die of lung cancer than of colon, breast, and prostate cancers, combined. Out of all types of lung … Read More

Toronto, Ontario – February 26, 2018 Theralase® Technologies Inc. (the “Company”) (TSXV: TLT) (OTCQX: TLTFF) announced today that the Company and Roger Dumoulin-White, former Chairman, President and Chief Executive Officer, have entered into a settlement agreement (“Agreement”) with Staff of the Ontario Securities Commission (“OSC”). This Agreement resolves issues relating to the Company’s continuous disclosure between November 3, 2006 and August 29, 2017 (“Time Period”) and specifically resolves: (a) that the Company did not update or supplement certain disclosed forward?looking information with additional mandated disclosure (including identification of assumptions, cautions and material risk factors) in connection with: (i) various statements in its public disclosure (including news releases and MD&As filed on the System for Electronic Document Analysis and Retrieval (“SEDAR”) and marketing materials posted on its website and elsewhere on the Internet), in which it rolled forward the launch date of the TLC-2000 therapeutic laser (“TLC-2000”) in 30-day to five … Read More

Toronto, Ontario – February 9, 2018 Theralase Technologies Inc. (“Theralase®” or the “Company”) (TLT: TSXV) (TLTFF: OTCQX), a clinical stage pharmaceutical company dedicated to the research and development of patented, light activated Photo Dynamic Compounds (“PDCs”) and their associated drug formulations for the safe and effective destruction of various cancers, announced today that the sixth patient in a nine patient Phase Ib Non-Muscle Invasive Bladder Cancer (“NMIBC”) clinical study (“Study”) was enrolled and treated on February 7, 2018, using the Company’s anti-cancer technology. The Study is being used to evaluate the Company’s lead PDC drug for the primary endpoint of safety and tolerability with a secondary endpoint of pharmacokinetics (movement and exit of drug within tissue). The Study also includes an exploratory endpoint of efficacy; however, this will not be a determining factor in the success or failure of the Study. Three patients have been enrolled and treated at the … Read More

Toronto, Ontario – January 18, 2018 Theralase Technologies Inc. (“Theralase®” or the “Company”) (TLT: TSXV) (TLTFF: OTC), a leading biotech company focused on the commercialization of medical devices to eliminate pain and when used in conjunction with Photo Dynamic Compounds (“PDCs”) to destroy cancer, announced today that the fifth patient in a Phase Ib Non-Muscle Invasive Bladder (“NMIBC”) clinical study (“Study”) was enrolled and treated on January 10, 2018, using the Company’s anti-cancer Photo Dynamic Therapy (“PDT”) technology. The anti-cancer PDT treatment procedure involves the instillation of a water based solution of Theralase’s lead anti-cancer PDC, TLD-1433, through the urethra into the bladder of the patient, to allow the PDC to be preferentially absorbed by NMIBC tumours. The bladder is then drained of the solution, flushed with sterile water to remove non-absorbed solution and refilled with sterile water via a cystoscope. A fibre optic assembly, known as a Dosimetry Fibre … Read More

Toronto, Ontario – January 17, 2018 Theralase Technologies Inc. (“Theralase®” or the “Company”) (TSXV: TLT) (OTCQX: TLTFF), a biotech company focused on the commercialization of medical lasers to eliminate pain and the development of Photo Dynamic Compounds (“PDCs”) to destroy cancer has announced an optimization to the delivery schedule of its proprietary anti-cancer vaccine, increasing its efficacy in the destruction of brain cancer. The anti-cancer vaccine was evaluated in a rat glioma (“RG2”) animal model, an established model of Glioblastoma Multiforme (“GBM”), a deadly form of human brain cancer. As originally disclosed, the anti-cancer vaccine was created by exposing RG2 cells to patented stressors extracorporeally (outside the body) and then injecting this anti-cancer vaccine into rats to delay the progression of brain glioma tumours. The previous data obtained in this model demonstrated an increase of 35% in the survival of animals that have been vaccinated twice versus control (non-vaccinated rats). In the latest research, rats were vaccinated twice and then … Read More

Toronto, Ontario – November 30, 2017 Theralase Technologies Inc. (“Theralase®” or the “Company”) (TSXV: TLT) (OTCQX: TLTFF), a leading biotech company focused on the commercialization of medical lasers to eliminate pain and the development of Photo Dynamic Compounds (“PDCs”) to destroy cancer has discovered that its Theralase® Cold Laser Therapy (“Theralase® CLT”) has been proven effective, preclinically, to enhance cancer cell destruction by standard cancer treatments. It was previously disclosed that one of the hallmarks of cancer cells is a change in cellular metabolism from an oxygenated process (mitochondrial respiration through the production of Adenosine Triphosphate (“ATP”) that relies on oxygen consumption) to an non-oxygenated process (glycolysis, an oxygen independent process), known as the “Warburg Effect”. Cancer cells modify their cellular metabolism to ensure their survival and proliferation, thus making them difficult to destroy by standard cancer treatments. Theralase has demonstrated, in previous research, preclinically, that its Theralase® CLT, using … Read More

Toronto, Ontario – November 29, 2017 Theralase Technologies Inc. (“Theralase®” or the “Company”) (TSXV: TLT) (OTCQX: TLTFF), a leading biotech company focused on the commercialization of medical devices to eliminate pain and the development of Photo Dynamic Compounds (“PDCs”) to destroy cancer, announced today that for the nine-month period ended September 30, 2017, total revenue increased to $1,354,254 from $1,206,726 for the same period in 2016, a 12% increase. In Canada, revenue increased 44% to $1,046,508 for the nine-month period ended September 30, 2017 from $728,277 for the nine-month period ended September 30, 2016. In the US, revenue decreased 32% to $272,305 from $399,445 and international revenue decreased 55% to $35,441 from $79,004 for the same periods. The increase in Canadian revenue in 2017 and the corresponding decrease in US and international revenue is attributable to the Company systematically building its sales and marketing teams commencing with the Canadian market, … Read More