Toronto, Ontario – November 27, 2017 Theralase Technologies Inc. (“Theralase®” or the “Company”) (TSXV: TLT) (OTCQX: TLTFF), a leading biotech company focused on the commercialization of medical lasers to eliminate pain and the development of Photo Dynamic Compounds (“PDCs”) to destroy cancer has announced that its Theralase® therapeutic laser technology platform has been proven preclinically to render cancer cells more susceptible to cancer destruction by Photo Dynamic Therapy (“PDT”), by reversing the Warburg Effect. One of the hallmarks of cancer cells is a change in cellular metabolism from mitochondrial respiration (the production of Adenosine TriPhosphate (“ATP”)) that relies on oxygen consumption to glycolysis, an oxygen independent process. Cancer cells systematically modify their metabolism to promote their: growth, survival, proliferation and long-term maintenance, without the need for molecular oxygen, thus making them difficult to destroy by traditional means. This common feature, amongst cancer cells, of a modified metabolism, is demonstrated by … Read More

Toronto, Ontario – November 22, 2017 Theralase Technologies Inc. (“Theralase®” or the “Company”) (TSXV: TLT) (OTCQX: TLTFF), a leading biotech company focused on the commercialization of medical lasers to eliminate pain and the development of Photo Dynamic Compounds (“PDCs”) to destroy cancer has announced that it has validated its new anti-cancer vaccine in an additional animal cancer model for colorectal cancer. The new anti-cancer vaccine was validated in a subcutaneous, colorectal cancer cell (CT.26 WT) mouse model, demonstrating that Theralase’s new anti-cancer vaccine is not solely limited to GlioBlastoma Multiforme (“GBM”) brain cancer cells (previously validated in a Rat Glioma (“RG2”) model), but is also able to be adapted to other types of cancer cell lines, in which the animal’s immune system is stimulated and subsequently programmed to hunt, recognize and destroy cancer cells of specific types. In Theralase conducted research, it was demonstrated that the new anti-cancer vaccine was able … Read More

Toronto, Ontario – November 21, 2017 Theralase Technologies Inc. (“Theralase®” or the “Company”) (TSXV: TLT) (OTCQX: TLTFF), a leading biotech company focused on the commercialization of medical devices to eliminate pain and the development of Photo Dynamic Compounds (“PDCs”) to destroy cancer, announced today that it has demonstrated 24 months long term stability of a second clinical batch of its lead anti-cancer PDC, TLD-1433. The confirmation of 24 months long term stability of the second clinical batch of TLD-1433 ensures that sufficient amount of the PDC will be available at Good Manufacturing Practice (“GMP”) levels for multiple Photo Dynamic Therapy (“PDT”) patient treatments during the planned Phase 2 clinical study for Non-Muscle Invasive Bladder Cancer (“NMIBC”). Stability studies are an essential component of pharmaceutical development, allowing evaluation of a drug’s stability under the influence of a variety of environmental factors such as: temperature, humidity and light. Data from these studies … Read More

Toronto, Ontario – November 20, 2017 Theralase Technologies Inc. (“Theralase®” or the “Company”) (TSXV: TLT) (OTCQX: TLTFF), a leading biotech company focused on the commercialization of medical lasers to eliminate pain and the development of Photo Dynamic Compounds (“PDCs”) to destroy cancer has announced the discovery of a new anti-cancer vaccine. This new anti-cancer vaccine was created by exposing Rat Glioma (RG2) cancer cells, representative of GlioBlastoma Multiforme (“GBM”), a deadly form of human brain cancer, to proprietary and patented stressors extracorporeally (outside the body) and then injecting this anti-cancer vaccine into rats to delay the progression of brain gliomas, utilizing a well-established animal model of GBM. The data obtained in this model by Theralase researchers demonstrated a significant increase of 35% in the survival of animals versus control (no vaccination). In previous research, Theralase reported that Rutherrin® (TLD-1433 + transferrin) injected intravenously (“IV”) into an animal diagnosed with GBM was able to effectively cross the Blood Brain Barrier (“BBB”) and localize preferentially to … Read More

Toronto, Ontario – November 13, 2017 Theralase Technologies Inc. (“Theralase®” or the “Company”) (TSXV: TLT) (OTCQX: TLTFF), a leading biotech company focused on the commercialization of medical lasers to eliminate pain and the development of Photo Dynamic Compounds (“PDCs”) to destroy cancer has recently identified a new platform of super potent anti-cancer drugs, or PDCs, discovered by Dr. Sherri McFarland, Ph.D., Professor, Department of Chemistry and Biochemistry, University of North Carolina at Greensboro, the original inventor of the Theralase licenced ruthenium-based PDCs. Dr. McFarland has discovered a new generation of PDCs, that are 10 billion times more potent in killing cancer cells than other tested PDCs. It only takes a few molecules of the new PDCs to kill cancer cells, in vitro, when activated by visible light. The new PDCs also exhibit very low, in vitro, dark cytotoxicity (cancer cell kill in the absence of light), providing a very low … Read More

Toronto, Ontario – November 8, 2017 First Four Patients Treated with Company’s Anti-Cancer Treatment Achieve Pre-Defined Primary, Secondary and Exploratory Outcome Measures Theralase Technologies Inc. (“Theralase®” or the “Company”) (TSXV: TLT) (OTCQX: TLTFF), a leading biotech company focused on the commercialization of medical lasers to eliminate pain and the development of Photo Dynamic Compounds (“PDCs”) to destroy cancer provides an interim data analysis on the first four patients treated, with the Company’s patented, light-activated PDC, TLD-1433, in a Phase Ib Non-Muscle Invasive Bladder Cancer (“NMIBC”) clinical study (“Study”), demonstrating successful achievement of the pre-defined primary, secondary and exploratory outcome measures. The Study entitled, “A Phase Ib Trial of Intravesical Photo Dynamic Therapy (“PDT”) in Patients with NMIBC at High Risk of Progression, Who are Refractory to Therapy with Bacillus Calmette-Guerin (“BCG”) and Who are Medically Unfit for or Refuse a Cystectomy” commenced treating patients in March 2017 and to date … Read More

Toronto, Ontario –October 31, 2017 Theralase Technologies Inc. (“Theralase®” or the “Company”) (TSXV: TLT) (OTCQX: TLTFF), a leading biotech company focused on the commercialization of medical lasers to eliminate pain and the development of Photo Dynamic Compounds (“PDCs”) to destroy cancer, announced today that a recent peer-reviewed paper entitled, “Novel Osmium-based Coordination Complexes as Photosensitizers for Panchromatic Photodynamic Therapy”, presenting research on Theralase licensed Osmium PDCs, has been independently reviewed by Dr. Edith C. Glazer in her recent paper entitled, “Panchromatic Osmium Complexes for Photodynamic Therapy: Solutions to Existing Problems and New Questions”. Edith C. Glazer, Ph.D., Associate Professor, Department of Biological Chemistry, University of Kentucky, Lexington, Kentucky provided an independent review of “Novel Osmium-based Coordination Complexes as Photosensitizers for Panchromatic Photodynamic Therapy” where she states that, “The validation of Osmium coordination complexes as photosensitizers for PDT, with very promising in vivo results, demonstrate radical improvements in survival following irradiation … Read More

Toronto, Ontario –October 30, 2017 Theralase Technologies Inc. (“Theralase®” or the “Company”) (TSXV: TLT) (OTCQX: TLTFF), a leading biotech company focused on the commercialization of medical lasers to eliminate pain and the development of Photo Dynamic Compounds (“PDCs”) to destroy cancer, announced today that its latest research will be presented at the 2018 International Society for Optical Engineering (“SPIE”) Photonics West to be held in San Francisco, California from January 27th to February 1st, 2018. SPIE Photonics West is the world’s largest photonics technologies event, consisting of three conferences and two world-class exhibitions. Every year over 20,000 participants attend to learn more about the latest research and technology in: translational biophotonics, global healthcare, understanding the brain, new lasers for manufacturing, applications of 3D technologies, photonics-based consumer products and other related subject matters. The “Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy XXVII” chairing committee have … Read More

Toronto, Ontario – September 25, 2017 Theralase Technologies Inc. (“Theralase®” or the “Company”) (TSXV: TLT) (OTCQX: TLTFF), a leading biotech company focused on the commercialization of medical lasers to eliminate pain and the development of Photo Dynamic Compounds (“PDCs”) to destroy cancer, announced today that its patented, lead anti-cancer drug, TLD-1433, when activated by X-rays, has been demonstrated preclinically, to be effective in the destruction of human GlioBlastoma Multiforme (“GBM”) cancer cells, a deadly form of brain cancer. According to the American Brain Tumor Association: “GBM are tumors that arise from astrocytes—the star-shaped cells that make up the “glue-like,” or supportive tissue of the brain. These tumors are usually highly malignant (cancerous) because the cells reproduce quickly, being supported by a large network of blood vessels.” “Nearly 80,000 new cases of primary brain tumors are expected to be diagnosed in the US this year, with approximately 32% of brain and central … Read More

Toronto, Ontario – September 19, 2017 Theralase Technologies Inc. (“Theralase®” or the “Company”) (TSXV: TLT) (OTCQX: TLTFF), a leading biotech company focused on the commercialization of medical lasers to eliminate pain and the development of Photo Dynamic Compounds (“PDCs”) to destroy cancer, announced today that its patented, lead anti-cancer drug, TLD-1433, has been proven effective in the destruction of a human pharyngeal carcinoma cell line, FaDu. In 2016, according to the American Society of Clinical Oncology (“ASCO”), an estimated 49,670 adults (35,720 men and 13,950 women) in the United States will be diagnosed with oral and oropharyngeal cancer. Rates of these cancers are more than twice as high in men, as in women. Cancer of the oral cavity is the ninth most common cancer among men. The average age of diagnosis is 62. The overall 5-year survival rate for people with oral or oropharyngeal cancer is 64%. It is estimated … Read More