Toronto, Ontario – April 9, 2015, Theralase Technologies Inc. (“Theralase” or the “Company”) (TLT:TSXV) (TLTFF: OTC Pink®) announced today that it has successfully manufactured the first pre-commercial batch of its lead anti-cancer Photo Dynamic Compound (“PDC”), TLD-1433, one of a new generation of unique light-activated anti-cancer compounds, specifically developed for the treatment of cancer. Drugs intended for in human clinical applications, such as TLD-1433, must be manufactured in accordance with Good Manufacturing Practices (“GMP”) standards. To achieve GMP standards, the normal process is a “scale-up” in production from a small quantity to validate the manufacturing process to larger pre-commercial quantities demonstrating manufacturing optimization and finally commercial quantities, produced under strict GMP standards, suitable for human use. Theralase has now successfully completed a major milestone in its anti-cancer program by having TLD-1433 successfully manufactured to pre-commercial quantities, allowing this quantity to be used in toxicology analyses, a key requirement for Health … Read More

Toronto, Ontario – April 2, 2015, Theralase Technologies Inc. (“Theralase” or the “Company”) (TLT:TSXV) (TLTFF: OTC Pink®) announced today that it recently held a pre “Clinical Trial Application” (“CTA”) consultation meeting with Health Canada (“HC”) with the objective of presenting its Photo Dynamic Therapy (“PDT”) technology in the treatment of cancer and seeking clinical trial design guidance. According to Health Canada, a clinical trial is defined as, “An investigation in respect of a drug, for use in humans, that involves human subjects, and that is intended to discover or verify the clinical, pharmacological or pharmacodynamic effects of the drug, identify any adverse events in respect of the drug, study the absorption, distribution, metabolism and excretion of the drug, or ascertain the safety or efficacy of the drug.” Roger Dumoulin-White, President and CEO presented Theralase’s corporate vision, preclinical data and Phase Ib clinical trial design for the Company’s lead Photo Dynamic … Read More

Toronto, Ontario – March 23, 2015, Theralase Technologies Inc. (“Theralase” or the “Company”) (TLT:TSXV) (TLTFF: OTC Pink®) announced today that it has partnered with CiToxLAB Safety and Health Research Laboratories (“CiToxLAB”) to provide toxicology and safety pharmacology for the lead anti-cancer Photo Dynamic Compound (“PDC”), TLD-1433. In order to further identify the safe dosing range of TLD-1433 to be used in human clinical trials for Non Muscle Invasive Bladder Cancer (“NMIBC”) planned for later this year, CitoxLAB will study the effects that TLD-1433 has on biological systems, alone and when light activated and analyze any interactions that these effects may have on the functioning of normal biological processes. Theralase is currently in development of a platform of anti-cancer Photo Dynamic Therapy (“PDT”) technologies for the destruction of numerous cancers, commencing with the destruction of NMIBC. Dr. Arkady Mandel, Chief Scientific Officer stated that, “I am pleased that we have partnered … Read More

Toronto, Ontario – March 11, 2015, Theralase Technologies Inc. (“Theralase” or the “Company”) (TLT:TSXV) (TLTFF: OTC Pink®) announced today confirmation of its strategic initiatives for 2015. On March 3, 2015, Theralase closed a prospectus financing, where the Company raised $CAN 8 million from US institutional and Canadian institutional and retail investors. Completed at a 20% discount to market, these funds are considered strategic to the Company as it has now solidified relationships with influential Canadian and US institutional investors that will prove to be invaluable down the road, as the Company executes on its strategic initiatives. Theralase is now fully funded to commence and complete its two core strategic initiatives in 2015. The first core strategic initiative for the Company is the launch of the next generation TLC-2000 “Cell Sensing” therapeutic laser system in Canada in April 2015 and in the US and Europe in 3Q2015. This technology will revolutionize … Read More

Toronto, Ontario – March 3, 2015, Theralase Technologies Inc. (“Theralase” or the “Corporation”) (TSXV:TLT) (OTC Pink®: TLTFF) is pleased to announce that it has closed its previously announced public offering  (the “Offering”) of units (each, a “Unit”).  On closing, the Corporation issued an aggregate of 18,181,817 Units at a price of $0.44 per Unit for aggregate gross proceeds of approximately $8,000,000.   Each Unit consists of one common share of the Corporation (each, a “Common Share”) and one common share purchase warrant (each, a “Warrant”). Each Warrant entitles the holder to acquire an additional Common Share at a price of $0.54 for a period of 60 months following the date of issuance. Euro Pacific Canada Inc. (the “Agent”) acted as agent in connection with the Offering pursuant to the terms and conditions of an agency agreement between the Corporation and the Agent dated February 25, 2015, as amended on March 3, 2015. Ladenburg … Read More

Toronto, Ontario – February 23, 2015, Theralase Technologies Inc. (“Theralase”) (TLT:TSXV) (TLTFF: OTC Pink®) announced today that it has identified a potential mechanism of how its lead anti-cancer drug works to destroy cancer cells and has also discovered a new application of the lead drug that may lead to the ability to detect the presence of cancer cells. Theralase’s lead Photo Dynamic Compound (“PDC”) TLD-1433, when combined with transferrin (a naturally occurring iron-binding blood plasma glycoprotein found in our body), was recently described in the provisional US patent application, entitled, “Transferrin Enhanced Photo Dynamic Therapy (“PDT”) Cancer Destruction”. Theralase’s Ruthenium based PDC TLD-1433 combined with transferrin has now been branded and trademarked by the Company, as RutherrinTM. RutherrinTM has demonstrated an ability to significantly increase the targeting of bladder cancer cells and in the process, significantly increase the efficacy and safety of the treatment procedure. TLD-1433 is able to bind … Read More

Toronto, Ontario – February 13, 2015, Theralase Technologies Inc. (“Theralase”) (TLT:TSXV) (TLTFF: OTC Pink®), a developer of advanced Photo Dynamic Therapy (“PDT”), for serious and life-threatening diseases, announced today that research on its Anti-Cancer Technology (“ACT”) platform involving its lead Photo Dynamic Compound (“PDC”) TLD-1433 has shown that it has significantly less skin toxicity than the Food and Drug Administration (“FDA”) approved PDC Photofrin®. Photofrin® has been documented to induce skin sensitivity in patient’s treated with the PDC to sunlight or bright lights after administration. Patients who receive Photofrin® will be photosensitive and must strictly avoid exposure of skin and eyes to direct sunlight or bright indoor light (i.e.: examination lamps, dental lamps, operating room lamps, unshaded light bulbs at close proximity, etc.) for at least 30 days post treatment. Some patients may remain photosensitive for up to 90 days or more. The photosensitivity is due to residual traces of the drug, which … Read More

Toronto, Ontario – February 11, 2015, Theralase Technologies Inc. (“Theralase”) (TLT:TSXV) (TLTFF: OTC Pink®) announced today that it has been ranked in the Toronto Stock Exchange Venture (“TSXV”) 50®. Every year, the TSX Venture 50® ranks the strongest companies on the TSXV by share price, trading volume, market capitalization and analyst coverage. The winning companies have seen impressive growth over the past year, offered strong return to their shareholders and are actively traded in the market. The TSX Venture 50® are the top 10 companies listed on the TSX Venture Exchange, in each of five major industry sectors – mining, oil & gas, technology & life sciences, diversified industries and clean technology – based on a ranking formula with equal weighting given to return on investment, market cap growth, trading volume and analyst coverage. All data was as of December 31, 2014. The ranking is being announced today with the … Read More

Toronto, Ontario – February 9, 2015, Theralase Technologies Inc. (“Theralase”) (TLT:TSXV) (TLTFF: OTC Pink®) announced today that it has successfully completed the design of the next generation therapeutic laser, the TLC-2000, and has filed for Health Canada approval via a Class 3 Medical Device Licence application. According to Health Canada guidelines, approval of a Class 3 Medical Device Licence is expected within approximately 75 days, which would indicate final approval on or about April 2015. Food and Drug Administration (“FDA”) and Conformité Européene (”CE”) approval of the TLC-2000 will be submitted in March 2015 and is expected on or about June 2015. The Theralase TLC-2000 is a next generation patented biofeedback therapeutic laser system that the Company has researched and systematically developed over the last 12 years, commencing with the issue of US patent 6,413,267 on July 2, 2002. Between 2003 to 2009, extensive scientific research of the laser biofeedback … Read More

Toronto, Ontario, February 3, 2015 /Theralase Technologies Inc. (“Theralase”) (TLT:TSXV) (TLTFF: OTC Pink(R)), a developer of advanced Photo Dynamic Therapy (“PDT“), for serious and life-threatening diseases, announced today that research on its Anti-Cancer Technology (“ACT“) platform involving its lead Photo Dynamic Compound (“PDC“) TLD-1433 has been peer reviewed and accepted for publication in the journal Photochemical & Photobiological Sciences. Results from the preclinical studies of Theralase’s PDT entitled, “A novel class of ruthenium-based photosensitizers effectively kills in-vitro cancer cells and in-vivo tumors” has been accepted for publication by the journal of Photochemical & Photobiological Sciences, a society-owned journal publishing high quality research on all aspects of photochemistry and photobiology. Preclinical research demonstrated that Theralase’s lead drug candidate TLD-1433 for advanced PDT: -Effectively destroyed cancer cells and tumors -Provided a clinically significant delay in tumor growth -Increased tumor-free survival in a model of colorectal cancer The research conducted by Dr. Lothar Lilge, a … Read More